Managing Rare And Complex Epilepsies – Part Ii

Rare and complex epilepsies represent a significant challenge in pediatrics. These forms of epilepsy are often associated with genetic syndromes and rare diseases, with an incidence of fewer than 5 cases per 10,000 people. In children, these conditions often manifest with drug-resistant seizures and complex neurological and cognitive disabilities, significantly impacting the quality of life for both patients and their families.

In recent years, advances in medical genetics have allowed for a better understanding of the molecular bases of many forms of pediatric epilepsy. The identification of mutations in specific genes has led to new diagnostic and therapeutic approaches, paving the way for precision medicine. This approach enables clinical management to be directed not only based on the clinical and electroencephalographic characteristics of the patient but also according to the specific genetic profile, thereby improving the effectiveness of therapies and optimizing the child's quality of life.

The objective of the conference is to deepen knowledge about rare and complex epilepsies in childhood, with a specific focus on genetic forms and new targeted treatments. Real clinical cases will be discussed, and diagnostic pathways will be analyzed, including next-generation sequencing (NGS) technologies, the interpretation of genetic data, and their impact on therapeutic decisions. Additionally, the multidisciplinary approach necessary to manage the psychiatric, cognitive, and behavioral comorbidities that often accompany these forms of epilepsy will be evaluated.

Through this event, participants will receive scientific and practical updates to guide them in the integrated and personalized management of rare and complex epilepsies in pediatric patients. The ultimate goal is to contribute to comprehensive patient care and enhance future therapeutic prospects.